INT279624

Context Info Confidence 0.18 First Reported 2009 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.67 Pain Relevance 0

extracellular space (Gpx3) oxidoreductase activity (Gpx3) extracellular region (Gpx3)

Anatomy Link Frequency meibomian gland 1 urine 1 Gpx3 (Mus musculus)

Pain Link Frequency Relevance Heat anesthesia 1 30.88 Inflammation 5 5.00 Central nervous system 2 5.00 potassium channel 2 5.00 antagonist 2 5.00 addiction 2 5.00 metalloproteinase 2 5.00 chemokine 2 5.00 Spinal cord 1 5.00 TRP channel 1 5.00

Disease Link Frequency Relevance Heat Disorders Of The Lacrimal System 85 97.16 INFLAMMATION 5 5.00 Dry Eye 4 5.00 Eyelid Disease 2 5.00 Autoimmune Disease 2 5.00 Myelodysplastic Syndromes 2 5.00 Syndrome 2 5.00 Ganglion Cysts 2 5.00 Dislocations 1 5.00 Acne 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Moreover, testosterone administration increased the expression of 726 genes (e.g. glutathione peroxidase 3) and decreased the activity of 283 genes (e.g. small proline-rich protein 2A) in the meibomian gland (Table 1 and Table 3).

Negative_regulation (decreased) of glutathione peroxidase 3 in meibomian gland associated with disorders of the lacrimal system

1) Confidence 0.18 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2728565 Disease Relevance 0.67 Pain Relevance 0

Third, the removal of extracellular Ca2+ and Na+ eliminated the current induced by urine stimulation.

Negative_regulation (removal) of extracellular in urine

2) Confidence 0.01 Published 2010 Journal The Journal of General Physiology Section Body Doc Link PMC2806418 Disease Relevance 0 Pain Relevance 0

General Comments

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