INT279630

Context Info Confidence 0.13 First Reported 2009 Last Reported 2009 Negated 0 Speculated 2 Reported most in Body Documents 1 Total Number 2 Disease Relevance 1.07 Pain Relevance 0.09

molecular_function (Abpe) cellular_component (Abpe) biological_process (Abpe)

Anatomy Link Frequency meibomian glands 1 lacrimal 1 Abpe (Mus musculus)

Pain Link Frequency Relevance Heat antagonist 4 87.56 chemokine 4 14.08 Inflammation 10 5.00 metalloproteinase 4 5.00 Spinal cord 2 5.00 fibrosis 2 5.00 Cholecystokinin 2 5.00 Pain 2 5.00 Hippocampus 2 5.00

Disease Link Frequency Relevance Heat Disorders Of The Lacrimal System 170 100.00 Dry Eye 8 47.76 Metaplasia 2 35.56 Aging 2 31.52 Androgen Insensitivity 2 31.00 Eyelid Disease 4 20.68 INFLAMMATION 10 5.00 Autoimmune Disease 4 5.00 Syndrome 4 5.00 Acne 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Testosterone may also act indirectly, by regulating the release of anterior pituitary hormones that may influence the lacrimal and meibomian glands.

Spec (may) Regulation (influence) of lacrimal in meibomian glands associated with disorders of the lacrimal system

1) Confidence 0.13 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2728565 Disease Relevance 0.53 Pain Relevance 0.04

Testosterone may also act indirectly, by regulating the release of anterior pituitary hormones that may influence the lacrimal and meibomian glands.

Spec (may) Regulation (influence) of lacrimal in lacrimal associated with disorders of the lacrimal system

2) Confidence 0.04 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2728565 Disease Relevance 0.53 Pain Relevance 0.04

General Comments

This test has worked.