INT280634

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Nub1) cellular_component (Nub1) biological_process (Nub1)
Nub1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
corticosteroid 59 16.44 Low Low
dexamethasone 5 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 22 50.00 Quite Low
Diabetes Mellitus 7 5.00 Very Low Very Low Very Low
Exsanguination 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Metabolic Syndrome 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Frailty 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the first model as depicted in Figure 3C, DR(N) linearly stimulates the production of the enzyme mRNA whereas a biosignal (BS) derived from DR(N) is responsible for secondary inhibition of the production as given by:
Negative_regulation (biosignal) of BS
1) Confidence 0.05 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733100 Disease Relevance 0 Pain Relevance 0
The IC50_SREBPm and IC50_BS represent the concentrations of DR(N) and BS at which the corresponding production rates are reduced to 50% of baseline values.
Negative_regulation (reduced) of BS
2) Confidence 0.05 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733097 Disease Relevance 0 Pain Relevance 0

General Comments

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