INT280890

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Context Info
Confidence 0.46
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.35
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sox10) nucleus (Sox10) DNA binding (Sox10)
transcription factor binding (Sox10) cytoplasm (Sox10)
Sox10 (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 24 5.00 Very Low Very Low Very Low
nociceptor 8 5.00 Very Low Very Low Very Low
Spinal cord 6 5.00 Very Low Very Low Very Low
Nerve growth factor 5 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Calcitonin gene-related peptide 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 164 87.84 High High
Targeted Disruption 16 79.04 Quite High
Repression 1 58.32 Quite High
Carcinoma 14 50.00 Quite Low
Ganglion Cysts 24 5.00 Very Low Very Low Very Low
Nociception 9 5.00 Very Low Very Low Very Low
Adenocarcinoma 3 5.00 Very Low Very Low Very Low
Breast Cancer 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sox10+/rtTA neurospheres were transfected with the TREbi-Runx1-EYFP expression vector (Fig. 1D).
Positive_regulation (transfected) of Gene_expression (transfected) of Sox10
1) Confidence 0.46 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2733376 Disease Relevance 0.08 Pain Relevance 0
Notably, the expression of Sox10, a member of the SOX (SRY-related HMG-box) family of TFs, was significantly increased in the Thy1low compared to the Thy1high subset (Figure 13C), but was only slightly higher in the CD24alow subset as compared to the CD24ahigh subset (Figure 13B).
Positive_regulation (increased) of Gene_expression (expression) of Sox10
2) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2920333 Disease Relevance 0.28 Pain Relevance 0

General Comments

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