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Context Info
Confidence 0.00
First Reported 1989
Last Reported 1989
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (CYP1A2, CYP2D6) oxidoreductase activity (CYP1A2, CYP2D6) endoplasmic reticulum (CYP1A2, CYP2D6)
mitochondrion (CYP2D6) enzyme binding (CYP1A2)
CYP1A2 (Homo sapiens)
CYP2D6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 17 98.94 Very High Very High Very High
alcohol 1 27.44 Quite Low
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Toxicity 1 43.00 Quite Low
Necrosis 1 27.08 Quite Low
Hepatotoxicity 2 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The extensive APAP-oxidizing capacity of this hamster P450, designated P450IA2 based upon its similarity to rat P450d and rabbit form 4 in terms of NH2-terminal amino acid sequence, spectral characteristics, immunochemical properties, and inducibility by BNF, agrees with previous reports concerning the APAP substrate specificity of the rat and rabbit P450IA2 proteins.
P450IA2 Binding (similarity) of P450d associated with paracetamol
1) Confidence 0.00 Published 1989 Journal Arch. Biochem. Biophys. Section Abstract Doc Link 2729995 Disease Relevance 0 Pain Relevance 0.70

General Comments

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