INT28244

Context Info Confidence 0.96 First Reported 1986 Last Reported 1989 Negated 0 Speculated 0 Reported most in Abstract Documents 7 Total Number 8 Disease Relevance 0.89 Pain Relevance 1.11

extracellular region (TCN1)

TCN1 (Homo sapiens)

Pain Link Frequency Relevance Heat Chronic pancreatitis 22 97.00

Disease Link Frequency Relevance Heat Pancreatitis 22 97.00 Steatorrhea 3 47.08

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The intestinal juice from patients and controls degraded 34.7 +/- 32.3% and 95.2 +/- 7.2% of holohaptocorrin, respectively.

Protein_catabolism (degraded) of haptocorrin

1) Confidence 0.96 Published 1986 Journal Am. J. Clin. Nutr. Section Abstract Doc Link 3728364 Disease Relevance 0.26 Pain Relevance 0.31

The percentage of degraded haptocorrin was estimated from the proportion of labelled cyanocobalamin that was transferred from haptocorrin to intrinsic factor.

Protein_catabolism (degraded) of haptocorrin

2) Confidence 0.41 Published 1986 Journal Lancet Section Abstract Doc Link 2876185 Disease Relevance 0.09 Pain Relevance 0.09

An in-vitro test of degradation of haptocorrin, a cobalamin-binding glycoprotein, was used to diagnose exocrine pancreatic dysfunction.

Protein_catabolism (degradation) of haptocorrin

3) Confidence 0.41 Published 1986 Journal Lancet Section Abstract Doc Link 2876185 Disease Relevance 0 Pain Relevance 0

In-vitro test of haptocorrin degradation for biological diagnosis of exocrine pancreatic dysfunction using duodenal juice collected during endoscopy.

Protein_catabolism (degradation) of haptocorrin

4) Confidence 0.24 Published 1986 Journal Lancet Section Title Doc Link 2876185 Disease Relevance 0.07 Pain Relevance 0.07

This test measures the transfer of labelled cobalamin from haptocorrin to the intrinsic factor which is provoked by the degradation of the haptocorrin by proteases in the duodenal juice.

Protein_catabolism (degradation) of haptocorrin

5) Confidence 0.21 Published 1989 Journal Gastroenterol. Clin. Biol. Section Abstract Doc Link 2737391 Disease Relevance 0.09 Pain Relevance 0.09

These percentages were correlated with the Schilling test and with the ability of intestinal juice to degrade haptocorrin.

Protein_catabolism (degrade) of haptocorrin

6) Confidence 0.21 Published 1986 Journal Am. J. Clin. Nutr. Section Abstract Doc Link 3728364 Disease Relevance 0.22 Pain Relevance 0.39

[Evaluation of exocrine pancreatic function by the haptocorrin degradation test of the duodenal fluid collected by endoscopy].

Protein_catabolism (degradation) of haptocorrin

7) Confidence 0.12 Published 1989 Journal Gastroenterol. Clin. Biol. Section Title Doc Link 2737391 Disease Relevance 0.07 Pain Relevance 0.07

In this study we have attempted to improve a new test: the test of haptocorrin degradation (THD).

Protein_catabolism (degradation) of haptocorrin

8) Confidence 0.12 Published 1989 Journal Gastroenterol. Clin. Biol. Section Abstract Doc Link 2737391 Disease Relevance 0.08 Pain Relevance 0.08

General Comments

This test has worked.