INT282557

Context Info Confidence 0.07 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.23 Pain Relevance 0

nucleolus (NANOG, REXO1) nucleus (NANOG, REXO1) cell differentiation (NANOG) cell proliferation (NANOG) intracellular (REXO1) embryo development (NANOG)

NANOG (Homo sapiens) REXO1 (Homo sapiens)

Pain Link Frequency Relevance Heat Potency 4 5.00 tetrodotoxin 3 5.00 Action potential 3 5.00 Sciatic nerve 3 5.00 Hippocampus 2 5.00 anesthesia 1 5.00 withdrawal 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 7 58.56 Chromosome Aberrations 1 57.60 Death 4 55.72 Obesity 4 50.00 Stress 3 24.64 Brain Injury 3 5.00 Targeted Disruption 2 5.00 Disease 2 5.00 Teratoma 2 5.00 Adhesions 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Our results showed that Oct4/ATSC can increase developmental potential following reprogramming via the overexpression of the embryonic transcription factors, Rex1, Oct4, and Oct4-dependent Nanog and Sox2.

Nanog Regulation (dependent) of Rex1

1) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2747014 Disease Relevance 0.23 Pain Relevance 0

General Comments

This test has worked.