INT283233

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 2.22
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (EDNRA) signal transduction (EDNRA) aging (EDNRA)
plasma membrane (EDNRA) signal transducer activity (EDNRA)
EDNRA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 7 95.20 Very High Very High Very High
Dopamine 11 5.00 Very Low Very Low Very Low
cINOD 6 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 248 99.62 Very High Very High Very High
Hypoxia 29 99.36 Very High Very High Very High
Shock 5 96.56 Very High Very High Very High
INFLAMMATION 15 95.20 Very High Very High Very High
Necrosis 23 80.20 Quite High
Increased Venous Pressure Under Development 5 78.76 Quite High
Renal Disease 55 74.72 Quite High
Disease 5 54.60 Quite High
Chronic Renal Failure 23 5.00 Very Low Very Low Very Low
Hemolytic Uremic Syndrome 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mechanism of cellular injury in hypoxic/ischemic AKI is not known, but alterations in endothelin or nitric oxide regulation of vascular tone, ATP depletion and alterations in the cytoskeleton, changes in heat shock proteins, initiation of the inflammatory response and the generation of reactive oxygen and nitrogen molecules may each play a role in cell injury [31–48].
Spec (may) Regulation (alterations) of Spec (may) Regulation (regulation) of endothelin associated with inflammatory response, hypoxia, shock and injury
1) Confidence 0.04 Published 2008 Journal Pediatr Nephrol Section Body Doc Link PMC2756346 Disease Relevance 2.22 Pain Relevance 0.05

General Comments

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