INT283364

Context Info Confidence 0.13 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.78 Pain Relevance 0.05

HCC (Homo sapiens)

Pain Link Frequency Relevance Heat fibrosis 6 51.20 Inflammation 1 50.80 Bile 2 5.00 alcohol 2 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Familial Adenomatous Polyposis 104 100.00 Hepatocellular Cancer 51 100.00 Cancer 48 94.08 Colon Cancer 2 92.88 Hepatitis 3 84.72 Hepatitis Virus Infection 4 77.32 Metastasis 11 54.40 Cirrhosis 9 51.72 Fibrosis 4 51.20 INFLAMMATION 1 50.80

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These findings suggest that quantitative epigenetic changes are probably of clinical significance in hepatocarcinogenesis, but further post-transcriptional mechanisms must also be responsible for inactivation of the APC gene in HCC.

Positive_regulation (responsible) of Negative_regulation (inactivation) of HCC associated with hepatocellular cancer and familial adenomatous polyposis

1) Confidence 0.13 Published 2007 Journal J Cancer Res Clin Oncol Section Body Doc Link PMC2757596 Disease Relevance 1.78 Pain Relevance 0.05

General Comments

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