INT285032

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Context Info
Confidence 0.28
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Bnip3, Bax) cytoplasm (Bnip3, Bax) nucleus (Bnip3, Bax)
nucleoplasm (Bnip3) nuclear envelope (Bnip3) endoplasmic reticulum (Bax)
Anatomy Link Frequency
retina 1
Bnip3 (Rattus norvegicus)
Bax (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 32 90.72 High High
Central nervous system 2 5.72 Low Low
anesthesia 3 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 32 96.60 Very High Very High Very High
Death 7 95.52 Very High Very High Very High
Stress 3 94.00 High High
Coronary Artery Disease 1 90.72 High High
Hypoxia 1 78.56 Quite High
Retina Disease 17 53.12 Quite High
Cv Unclassified Under Development 11 42.80 Quite Low
Ocular Hypertension 8 26.88 Quite Low
Targeted Disruption 2 13.52 Low Low
Cv General 4 Under Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, it would be interesting to study Bnip3-induced activation of Bax and Bak and to analyze whether Bnip-3 could also be associated with the increase in apoptosis observed after I/R in the retina.
Bnip3 Positive_regulation (activation) of Bax in retina associated with apoptosis
1) Confidence 0.28 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2765238 Disease Relevance 0.77 Pain Relevance 0.07

General Comments

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