INT285185

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Context Info
Confidence 0.25
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.24
Pain Relevance 1.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ca2) extracellular space (Ca2) extracellular region (Cd2)
lyase activity (Ca2) protein complex (Cd2) response to stress (Ca2)
Ca2 (Rattus norvegicus)
Cd2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 216 90.92 High High
ASIC 54 43.48 Quite Low
antagonist 15 26.88 Quite Low
Pain 18 5.00 Very Low Very Low Very Low
Calcitonin gene-related peptide 18 5.00 Very Low Very Low Very Low
Nerve growth factor 9 5.00 Very Low Very Low Very Low
tissue acidosis 6 5.00 Very Low Very Low Very Low
bradykinin 6 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
halothane 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acidosis 423 79.52 Quite High
Hypoxia 186 50.00 Quite Low
Cv Unclassified Under Development 54 5.00 Very Low Very Low Very Low
Pain 18 5.00 Very Low Very Low Very Low
Acid Base Imbalance 15 5.00 Very Low Very Low Very Low
Lactic Acidosis 15 5.00 Very Low Very Low Very Low
Overdose 3 5.00 Very Low Very Low Very Low
Coronary Artery Disease 3 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
Shock 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cd2+ binding to Fura-2 has similar effects on its fluorescence to those of Ca2+ binding but Fura-2 has a much greater affinity for Cd2+ than for Ca2+ [36].
Ca2 Binding (affinity) of Cd2
1) Confidence 0.25 Published 2009 Journal Pflugers Arch Section Body Doc Link PMC2765625 Disease Relevance 0.05 Pain Relevance 0.49
Cd2+ binding to Fura-2 has similar effects on its fluorescence to those of Ca2+ binding but Fura-2 has a much greater affinity for Cd2+ than for Ca2+ [36].
Ca2 Binding (affinity) of Cd2
2) Confidence 0.25 Published 2009 Journal Pflugers Arch Section Body Doc Link PMC2765625 Disease Relevance 0.05 Pain Relevance 0.49
Once inside the cell, Cd2+ will inevitably bind to Fura-2, as this has a much higher affinity for Cd2+ than for Ca2+, which will cause similar changes in Fura-2 fluorescence to that observed with Ca2+ [36].
Ca2 Binding (affinity) of Cd2
3) Confidence 0.25 Published 2009 Journal Pflugers Arch Section Body Doc Link PMC2765625 Disease Relevance 0.14 Pain Relevance 0.22

General Comments

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