INT285289

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Context Info
Confidence 0.23
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.44
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TNF, Icam1) plasma membrane (TNF, Icam1) signal transduction (TNF)
extracellular region (TNF) cell adhesion (Icam1) intracellular (TNF)
Anatomy Link Frequency
lymphocytes 1
TNF (Homo sapiens)
Icam1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 13 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Melanoma 55 99.40 Very High Very High Very High
Cancer 188 97.04 Very High Very High Very High
Adhesions 3 95.88 Very High Very High Very High
Targeted Disruption 1 50.88 Quite High
Necrosis 14 50.00 Quite Low
Fibrosarcoma 1 43.08 Quite Low
Sarcoma 180 2 37.84 Quite Low
Apoptosis 8 17.36 Low Low
Toxicity 2 8.28 Low Low
Metastasis 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TNF can also upregulate ICAM-1 shedding from melanoma cells and thus inhibit, by soluble ICAM-1, adherence of NK lymphocytes to tumor cells [6].
TNF Positive_regulation (upregulate) of ICAM-1 in lymphocytes associated with cancer and melanoma
1) Confidence 0.23 Published 2007 Journal Arch Immunol Ther Exp (Warsz) Section Body Doc Link PMC2766459 Disease Relevance 1.44 Pain Relevance 0

General Comments

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