INT285381

Context Info Confidence 0.12 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.08 Pain Relevance 0.06

transport (Scn11a) Golgi apparatus (Chst10) plasma membrane (Scn11a) transmembrane transport (Scn11a)

Scn11a (Mus musculus) Chst10 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Morphine 1 62.72 Potency 1 41.56 Bile 11 5.00 diclofenac 2 5.00 agonist 2 5.00 adenocard 1 5.00

Disease Link Frequency Relevance Heat Targeted Disruption 15 82.40 Severe Combined Immunodeficiency 6 26.00 Hepatitis C Virus Infection 9 5.00 Hepatitis B Virus Infection 8 5.00 Infection 6 5.00 Hepatitis 4 5.00 Viremia 3 5.00 Liver Disease 2 5.00 Liver Cancer 2 5.00 Body Weight 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The major hepatic phase II enzymes in humans are UDP-glucuronosyltransferase (UGT), which is responsible for glucuronidation; sulfotransferase (SULT), for sulfation; N-acetyltransferase (NAT), for acetylation; and glutathione S-transferase (GST), for glutathione conjugation.

NAT Positive_regulation (responsible) of Localization (sulfotransferase) of SULT

1) Confidence 0.12 Published 2009 Journal PPAR Research Section Body Doc Link PMC2768028 Disease Relevance 0.08 Pain Relevance 0.06

General Comments

This test has worked.