INT285862

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.80
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (GRM7) signal transducer activity (GRM7)
GRM7 (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate 9 97.24 Very High Very High Very High
Glutamate receptor 4 91.92 High High
Hyperalgesia 4 87.04 High High
nociceptor 3 84.96 Quite High
nMDA receptor 4 80.92 Quite High
Pain 31 79.60 Quite High
Lasting pain 2 76.72 Quite High
central sensitization 4 74.72 Quite High
depression 9 59.84 Quite High
Neurotransmitter 9 59.64 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 5 87.44 High High
Pain 30 79.60 Quite High
Nociception 17 61.92 Quite High
Headache 77 60.64 Quite High
Depression 9 59.84 Quite High
Cv General 2 Under Development 1 51.24 Quite High
Vertigo 1 50.16 Quite High
Dizziness 1 49.12 Quite Low
Pressure And Volume Under Development 2 41.44 Quite Low
Pallor 1 38.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The phosphorilation of intracellular substrates like ionic channels is able to modulate different phases of the synaptic transmission and the activation of mGlu 5 can increase the sensitivity of ionotropic receptors also for the glutamate itself.
Positive_regulation (activation) of mGlu associated with glutamate
1) Confidence 0.01 Published 2009 Journal The Open Neurology Journal Section Body Doc Link PMC2771268 Disease Relevance 0.80 Pain Relevance 0.82

General Comments

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