INT28641

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Context Info
Confidence 0.45
First Reported 1989
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.90
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CXCR2) plasma membrane (CXCR2) intracellular (CXCR2)
signal transducer activity (CXCR2)
Anatomy Link Frequency
neutrophils 2
CXCR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
narcan 14 99.82 Very High Very High Very High
chemokine 1 98.00 Very High Very High Very High
Inflammation 10 94.28 High High
cytokine 4 87.32 High High
antagonist 2 64.28 Quite High
opiate 1 63.48 Quite High
Enkephalin 1 62.24 Quite High
Inflammatory marker 2 37.60 Quite Low
Inflammatory response 1 32.68 Quite Low
nud 5 23.52 Low Low
Disease Link Frequency Relevance Heat
Gastritis 5 97.84 Very High Very High Very High
Duodenal Ulcer 8 97.28 Very High Very High Very High
Infection 39 96.40 Very High Very High Very High
Gastroesophageal Reflux Disease 76 95.56 Very High Very High Very High
INFLAMMATION 14 94.28 High High
Disease 14 62.72 Quite High
Ulcers 14 50.00 Quite Low
Sprains And Strains 13 35.68 Quite Low
Dyspepsia 5 23.52 Low Low
Adenocarcinoma 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NAL did not affect spontaneous IL-2 receptor expression and it moderately increased PHA-induced IL-2 receptor expression in most of the investigated persons.
Neg (not) Spec (investigated) Regulation (affect) of Gene_expression (expression) of IL-2 receptor associated with narcan
1) Confidence 0.45 Published 1989 Journal Int. J. Immunopharmacol. Section Abstract Doc Link 2784786 Disease Relevance 0.38 Pain Relevance 0.70
But, their expression is dependent on the corresponding expression of their receptors (CXCR1 and CXCR2) on neutrophils.95 IL-8 may influence development of gastritis and duodenal ulcer in patients with H. pylori infection.96,97
Regulation (dependent) of Gene_expression (expression) of CXCR2 in neutrophils associated with duodenal ulcer, gastritis and infection
2) Confidence 0.05 Published 2010 Journal Journal of Neurogastroenterology and Motility Section Body Doc Link PMC2912116 Disease Relevance 1.53 Pain Relevance 0.21

General Comments

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