INT286694

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Context Info
Confidence 0.26
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Slc6a4) endosome (Slc6a4) transport (Slc6a4)
plasma membrane (Slc6a4)
Slc6a4 (Mus musculus)
Pain Link Frequency Relevance Heat
Ventral tegmentum 8 97.60 Very High Very High Very High
Nucleus accumbens 64 97.28 Very High Very High Very High
Dopamine 98 96.64 Very High Very High Very High
Central nervous system 2 66.92 Quite High
antagonist 22 63.84 Quite High
sSRI 10 54.84 Quite High
Serotonin 24 50.00 Quite Low
addiction 8 16.40 Low Low
midbrain 2 5.96 Low Low
Eae 18 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Drug Dependence 8 16.40 Low Low
Targeted Disruption 8 5.00 Very Low Very Low Very Low
Recurrence 4 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low
Fever 2 5.00 Very Low Very Low Very Low
Serotonin Syndrome 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, functional pre-synaptic 5-HT2B receptors are required for MDMA-induced SERT dependent 5-HT release in vivo and in vitro [19].
Positive_regulation (induced) of Localization (release) of SERT
1) Confidence 0.26 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2775951 Disease Relevance 0 Pain Relevance 0.45
Indeed, functional pre-synaptic 5-HT2B receptors are required for MDMA-induced SERT dependent 5-HT release in vivo and in vitro [19].
Positive_regulation (required) of Localization (release) of SERT
2) Confidence 0.26 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2775951 Disease Relevance 0 Pain Relevance 0.45

General Comments

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