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Context Info
Confidence 0.42
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.53
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Musk) plasma membrane (Musk) kinase activity (Musk)
Anatomy Link Frequency
muscle 2
Musk (Mus musculus)
Pain Link Frequency Relevance Heat
Action potential 1 17.68 Low Low
anesthesia 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Myasthenic Syndromes 22 97.04 Very High Very High Very High
Adhesions 2 81.64 Quite High
Respiratory Failure 2 73.92 Quite High
Hypoxia 2 68.20 Quite High
Cyanosis 1 37.12 Quite Low
Patent Ductus Arteriosus 1 35.04 Quite Low
Syndrome 3 12.32 Low Low
Disease 1 9.44 Low Low
Targeted Disruption 7 5.00 Very Low Very Low Very Low
Myasthenia Gravis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These mutations impair the expression and stability of MuSK, diminish agrin-dependent MuSK phosphorylation and AChR clustering, and fail to co-immunoprecipitate with Dok-7 but not with Lrp4 or Tid1.
Negative_regulation (impair) of Gene_expression (expression) of MuSK
1) Confidence 0.42 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2876883 Disease Relevance 0.38 Pain Relevance 0
Thus, muscle-specific deletion of the p38?
Negative_regulation (Thus) of Gene_expression (deletion) of muscle-specific in muscle
2) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2775956 Disease Relevance 0.15 Pain Relevance 0

General Comments

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