INT286831

Context Info Confidence 0.38 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.08 Pain Relevance 0

transport (Kcnma1) endoplasmic reticulum (Kcnma1) plasma membrane (Kcnma1) transmembrane transport (Kcnma1)

Kcnma1 (Mus musculus)

Pain Link Frequency Relevance Heat depression 1 15.76 Somatostatin 3 5.00 ketamine 2 5.00 anesthesia 2 5.00 potassium channel 2 5.00 Dermatone 1 5.00 Pyramidal cell 1 5.00 lidocaine 1 5.00 gABA 1 5.00 Action potential 1 5.00

Disease Link Frequency Relevance Heat Ataxia 21 76.56 Depression 1 15.76 Camurati-engelmann Disease 2 5.00 Shock 1 5.00 Stress 1 5.00 Congenital Anomalies 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Maximal activation of BK channels (alias maxiK, KCNMA1, KCa1.1 or slowpoke) requires both membrane depolarization and increased intracellular Ca2+[4], [5].

Positive_regulation (increased) of Positive_regulation (activation) of KCNMA1

1) Confidence 0.38 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2776494 Disease Relevance 0.08 Pain Relevance 0

General Comments

This test has worked.