INT28722

Context Info Confidence 0.11 First Reported 1989 Last Reported 1989 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0.14 Pain Relevance 0.18

plasma membrane (Hdac11) nucleus (Hdac11) transcription factor binding (Hdac11) cytoplasm (Hdac11)

T2 (Mus musculus) Hdac11 (Mus musculus)

Pain Link Frequency Relevance Heat tetrodotoxin 2 94.60

Disease Link Frequency Relevance Heat Squamous Cell Carcinoma 2 71.36

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The binding of HD11 to T-2 conjugated to bovine serum albumin was inhibited by free T-2 toxin but not by the water-soluble heterocyclic guanidines saxitoxin and tetrodotoxin.

T-2 Binding (binding) of HD11 associated with tetrodotoxin

1) Confidence 0.11 Published 1989 Journal Toxicol. Appl. Pharmacol. Section Abstract Doc Link 2789441 Disease Relevance 0.07 Pain Relevance 0.09

The antibody, designated HD11, specifically bound T-2 mycotoxin.

T-2 Binding (bound) of HD11

2) Confidence 0.09 Published 1989 Journal Toxicol. Appl. Pharmacol. Section Abstract Doc Link 2789441 Disease Relevance 0.07 Pain Relevance 0.09

General Comments

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