INT288519

Context Info Confidence 0.30 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.90 Pain Relevance 1.26

cytosol (Gch1) nucleolus (Gch1) nucleus (Gch1) protein complex assembly (Gch1) protein complex (Gch1) cytoplasm (Gch1)

Gch1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Lasting pain 2 98.92 GCH1 112 96.20 Neuropathic pain 28 94.20 Pain 92 88.44 dorsal root ganglion 32 5.00 Sciatic nerve 30 5.00 Inflammation 20 5.00 Spinal cord 12 5.00 Tetrahydrobiopterin 8 5.00 Dorsal horn 8 5.00

Disease Link Frequency Relevance Heat Pain 104 98.92 Neuropathic Pain 34 94.20 Neurodegenerative Disease 4 39.20 Cytomegalovirus Infection 4 28.00 Ganglion Cysts 32 5.00 Nervous System Injury 26 5.00 INFLAMMATION 20 5.00 Hyperalgesia 2 5.00 Toxicity 2 5.00 Dystonia 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Effects of gene silencing of rat GTP cyclohydrolase (rGCH1) with siRNA and shRNA

GTP cyclohydrolase Binding (silencing) of

1) Confidence 0.30 Published 2009 Journal Mol Pain Section Body Doc Link PMC2785765 Disease Relevance 0.45 Pain Relevance 0.63

Effects of gene silencing of rat GTP cyclohydrolase (rGCH1) with siRNA and shRNA

rGCH1 Binding (silencing) of

2) Confidence 0.30 Published 2009 Journal Mol Pain Section Body Doc Link PMC2785765 Disease Relevance 0.45 Pain Relevance 0.63

General Comments

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