INT288617

Context Info Confidence 0.19 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.73 Pain Relevance 0

signal transduction (CSF2RB, Epor) plasma membrane (CSF2RB, Epor) extracellular region (Epor) embryo development (Epor)

CSF2RB (Homo sapiens) Epor (Mus musculus)

Pain Link Frequency Relevance Heat medulla 35 50.00 cva 7 5.00 anesthesia 2 5.00 Bioavailability 2 5.00 midbrain 1 5.00 Inflammation 1 5.00 Inflammatory response 1 5.00 Calcium channel 1 5.00

Disease Link Frequency Relevance Heat Neurological Disease 2 95.72 Malaria 66 78.56 Edema 4 77.84 Cerebral Malaria 30 67.20 Pressure And Volume Under Development 1 64.32 Hypoxia 8 61.28 Cerebral Hypoxia 1 52.24 Brain Injury 5 40.36 Injury 13 5.00 Death 8 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Although no studies have directly shown a role for CD131 in binding Epo to the surface of any cell (reviewed in [41]), CD131 has been shown to physically and/or functionally associate with EpoR and coexpression of these receptors have been observed using immunohistochemistry in tissue sections from neurological disease models in animals [28,42,43].

CD131 Binding (associate) of EpoR associated with neurological disease

1) Confidence 0.19 Published 2009 Journal Malar J Section Body Doc Link PMC2785829 Disease Relevance 0.73 Pain Relevance 0

General Comments

This test has worked.