INT288813

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Context Info
Confidence 0.69
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.23
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Rasgrf2) plasma membrane (Rasgrf2) intracellular (Rasgrf2)
cytoplasm (Rasgrf2)
Anatomy Link Frequency
colon 4
Rasgrf2 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 9.76 Low Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 4 97.88 Very High Very High Very High
Cancer 130 97.76 Very High Very High Very High
Precursor Cell Lymphoblastic Leukemia-lymphoma 12 74.40 Quite High
Targeted Disruption 2 50.00 Quite Low
Sprains And Strains 10 35.00 Quite Low
Lymphatic System Cancer 88 29.44 Quite Low
Leukemia 42 5.00 Very Low Very Low Very Low
Disease 14 5.00 Very Low Very Low Very Low
Chronic Lymphoid Leukemia 8 5.00 Very Low Very Low Very Low
Lymphopenia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with this possibility, it has been recently demonstrated that the overexpression of RasGRF2 affects negatively the transforming properties of a colon cancer cell line [15].
Positive_regulation (overexpression) of Gene_expression (overexpression) of RasGRF2 in colon associated with colon cancer
1) Confidence 0.69 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2788417 Disease Relevance 0.54 Pain Relevance 0
Moreover, it has been demonstrated that the overexpression of RasGRF2 negatively affects the transforming properties of a colon cancer cell line [15].
Positive_regulation (overexpression) of Gene_expression (overexpression) of RasGRF2 in colon associated with colon cancer
2) Confidence 0.50 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2788417 Disease Relevance 0.69 Pain Relevance 0

General Comments

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