INT290086

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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.60
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CYFIP2)
Anatomy Mention Frequency
monocytes 1
fibroblasts 1
CYFIP2 (Homo sapiens)
Pain Term Frequency Confidence Heat
cytokine 12 41.12 Quite Low
chemokine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
imagery 10 5.00 Very Low Very Low Very Low
Disease Term Frequency Confidence Heat
Muscular Dystrophy 4 100.00 Very High Very High Very High
Adhesions 6 100.00 Very High Very High Very High
Choroideremia 332 98.92 Very High Very High Very High
Stress 10 47.52 Quite Low
Toxicity 6 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Retina Disease 4 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Functional categories affected in both fibroblasts and monocytes of CHM patients included a large group of genes involved in regulation of cell adhesion and motility (NCAM-2, FMN1, ANKRD28, CSF3R, DMD, MLLT4, DPP4, TSPAN5, CD114, DMD, CYFIP2, WNT5A, MMP7), immune response (IL1, CC2, CFI, ELOVL2), regulation of trafficking and exocytosis (RGS11, SYT 6, GBF1) and transcriptional regulation (HOXD11, MRO, NRG1, NLRC3, NR2F6, SALL1, DIP2A, RSOPO2) (Fig. 7A).
Regulation (regulation) of CYFIP2 in monocytes associated with muscular dystrophy, choroideremia and adhesions
1) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2793004 Disease Relevance 0.80 Pain Relevance 0
Functional categories affected in both fibroblasts and monocytes of CHM patients included a large group of genes involved in regulation of cell adhesion and motility (NCAM-2, FMN1, ANKRD28, CSF3R, DMD, MLLT4, DPP4, TSPAN5, CD114, DMD, CYFIP2, WNT5A, MMP7), immune response (IL1, CC2, CFI, ELOVL2), regulation of trafficking and exocytosis (RGS11, SYT 6, GBF1) and transcriptional regulation (HOXD11, MRO, NRG1, NLRC3, NR2F6, SALL1, DIP2A, RSOPO2) (Fig. 7A).
Regulation (regulation) of CYFIP2 in fibroblasts associated with muscular dystrophy, choroideremia and adhesions
2) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2793004 Disease Relevance 0.80 Pain Relevance 0

General Comments

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