INT291240

Context Info Confidence 0.16 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.72 Pain Relevance 0.32

cytoplasm (Map3k8, Mapk1) signal transduction (Map3k8, Mapk1) cell cycle (Map3k8, Mapk1) kinase activity (Map3k8, Mapk1) nucleoplasm (Mapk1) mitochondrion (Mapk1)

Map3k8 (Mus musculus) Mapk1 (Mus musculus)

Pain Link Frequency Relevance Heat Inflammatory stimuli 5 87.04 cytokine 39 81.12 Inflammation 26 79.28 Inflammatory mediators 2 22.80 tolerance 1 5.00 anesthesia 1 5.00 Kinase C 1 5.00

Disease Link Frequency Relevance Heat Obesity 106 90.96 INFLAMMATION 33 87.04 Insulin Resistance 10 60.96 Cancer 5 50.00 Necrosis 3 50.00 Diabetes Mellitus 8 5.00 Hypertension 1 5.00 Targeted Disruption 1 5.00 Impaired Glucose Tolerance 1 5.00 Dislocations 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Similarly, Tpl2 is dispensable for ERK activation induced by phorbol myristate acetate (PMA) (29).

Tpl2 Positive_regulation (dispensable) of Positive_regulation (activation) of ERK

1) Confidence 0.16 Published 2010 Journal Diabetes Section Body Doc Link PMC2797946 Disease Relevance 0.72 Pain Relevance 0.32

General Comments

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