INT292006

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 9
Disease Relevance 2.55
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ADSL) mitochondrion (ADSL) small molecule metabolic process (ADSL)
lyase activity (ADSL) cytoplasm (ADSL)
Anatomy Link Frequency
Paneth cell 2
ADSL (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 12 73.80 Quite High
Inflammation 67 68.92 Quite High
tolerance 6 56.08 Quite High
Potency 32 52.88 Quite High
Crohn's disease 40 5.00 Very Low Very Low Very Low
Neuropeptide 30 5.00 Very Low Very Low Very Low
cytokine 15 5.00 Very Low Very Low Very Low
Enkephalin 6 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fungal Infection 54 96.88 Very High Very High Very High
Helminth Infection 10 96.08 Very High Very High Very High
Targeted Disruption 12 93.12 High High
Injury 46 92.24 High High
Seborrhea 24 91.20 High High
Burns 29 84.36 Quite High
Sprains And Strains 30 78.52 Quite High
Death 21 71.20 Quite High
INFLAMMATION 59 68.92 Quite High
Colitis 4 61.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Employing fluorescence deconvolution microscopy to produce 3-dimensional, volume-rendered images (computer-generated virtual models)8,9 allowed for the determination of which specific cell type(s) produced or included specific AMPs.
Gene_expression (produced) of AMPs
1) Confidence 0.22 Published 2010 Journal Eplasty Section Body Doc Link PMC2803769 Disease Relevance 0.85 Pain Relevance 0
In general, AMPs are synthesized as precursors containing the active peptide segment, which is released by proteolytic processing, usually upon the removal of an anionic propiece [4].
Gene_expression (synthesized) of AMPs
2) Confidence 0.06 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2866484 Disease Relevance 0.11 Pain Relevance 0
A definitive classification scheme still needs to be agreed but most authorities recognise at least 3 main classes of conventional AMPs based on their secondary structure, namely: linear ?
Gene_expression (based) of AMPs
3) Confidence 0.05 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2866484 Disease Relevance 0.05 Pain Relevance 0
AMPs have been the best studied with respect to their localization in cells and tissues, their expression under different conditions [77] and during their life-history [78], their differential involvement in antimicrobial defence [79] and the distribution of different isoforms in individual animals [80].
Gene_expression (expression) of AMPs
4) Confidence 0.05 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2866484 Disease Relevance 0.25 Pain Relevance 0
Conventional AMPs
Gene_expression (Conventional) of AMPs
5) Confidence 0.05 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2866484 Disease Relevance 0.20 Pain Relevance 0
Other ascidian AMPs that form ?
Gene_expression (form) of AMPs
6) Confidence 0.05 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2866484 Disease Relevance 0 Pain Relevance 0.03
Miscellaneous AMPs
Gene_expression (Miscellaneous) of AMPs
7) Confidence 0.05 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2866484 Disease Relevance 0.19 Pain Relevance 0.03
Interestingly, expression of HD-5 exceeds expression levels of other AMPs produced by the Paneth cell (lysozyme and sPLa2) by a factor up to 100 [45].
Gene_expression (expression) of AMPs in Paneth cell
8) Confidence 0.04 Published 2010 Journal International Journal of Inflammation Section Body Doc Link PMC2992817 Disease Relevance 0.44 Pain Relevance 0.10
Interestingly, expression of HD-5 exceeds expression levels of other AMPs produced by the Paneth cell (lysozyme and sPLa2) by a factor up to 100 [45].
Gene_expression (produced) of AMPs in Paneth cell
9) Confidence 0.04 Published 2010 Journal International Journal of Inflammation Section Body Doc Link PMC2992817 Disease Relevance 0.45 Pain Relevance 0.10

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