INT292413

Context Info Confidence 0.00 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.88 Pain Relevance 0

molecular_function (Myo1f)

Myo1f (Mus musculus)

Pain Link Frequency Relevance Heat Bioavailability 2 26.12 anesthesia 3 5.00 depression 1 5.00 ischemia 1 5.00

Disease Link Frequency Relevance Heat Acidosis 1 99.54 Fatigue 17 97.84 Stress 2 96.16 Overdose 2 5.00 Cv Unclassified Under Development 1 5.00 Depression 1 5.00 Shock 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Acidosis and increased Pi each inhibit actin-myosin interaction, precipitating contractile failure, and this type of fatigue is also associated with oxidative stress (51).

Negative_regulation (inhibit) of actin-myosin Binding (interaction) of associated with stress, acidosis and fatigue

1) Confidence 0.00 Published 2010 Journal American Journal of Physiology - Regulatory, Integrative and Comparative Physiology Section Body Doc Link PMC2806206 Disease Relevance 0.88 Pain Relevance 0

General Comments

This test has worked.