INT292570

Context Info Confidence 0.07 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.80 Pain Relevance 0.28

plasma membrane (F2RL1, HTR1A) signal transducer activity (F2RL1, HTR1A) Golgi apparatus (F2RL1)

F2RL1 (Homo sapiens) HTR1A (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 20 98.44 Arthritis 2 62.40 IPN 2 61.52 agonist 26 5.00 antagonist 10 5.00 cytokine 8 5.00 Inflammatory response 2 5.00 Inflammatory mediators 2 5.00 chemokine 2 5.00 Potency 2 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 24 98.44 Disease 4 65.04 Arthritis 2 62.40 Inflammatory Pain 2 61.52 Colitis 2 59.76 Contact Dermatitis 2 55.20 Cv Unclassified Under Development 2 38.32 Reperfusion Injury 2 37.52 Cancer 4 5.00 Stress 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Proteinase-activated receptor-2 (PAR2), is a member of the G-protein coupled receptor (GPCR) subfamily typified by the thrombin receptor, PAR1 [1].

PAR2 Binding (member) of G-protein coupled receptor

1) Confidence 0.07 Published 2010 Journal Cellular Signalling Section Body Doc Link PMC2806525 Disease Relevance 0.40 Pain Relevance 0.14

Proteinase-activated receptor-2 (PAR2), is a member of the G-protein coupled receptor (GPCR) subfamily typified by the thrombin receptor, PAR1 [1].

Proteinase-activated receptor-2 Binding (member) of G-protein coupled receptor

2) Confidence 0.07 Published 2010 Journal Cellular Signalling Section Body Doc Link PMC2806525 Disease Relevance 0.40 Pain Relevance 0.14

General Comments

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