INT293122

Context Info Confidence 0.04 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.81 Pain Relevance 0.05

aging (Aqp2) protein complex (Aqp2) transmembrane transport (Aqp2) cytoplasm (Aqp2) response to stress (Avp) signal transducer activity (Avp)

Anatomy Link Frequency duct 2 Avp (Rattus norvegicus) Aqp2 (Rattus norvegicus)

Pain Link Frequency Relevance Heat medulla 1 94.68 isoflurane 4 5.00 anesthesia 3 5.00 antagonist 3 5.00 fibrosis 1 5.00 bradykinin 1 5.00

Disease Link Frequency Relevance Heat Chronic Renal Failure 124 97.12 Uremia 4 76.72 Congenital Anomalies 1 69.00 Hypertrophy 11 5.00 Natriuresis 2 5.00 Fibrosis 1 5.00 Disorders Of Creatine Metabolism 1 5.00 Bartter Syndrome 1 5.00 Hypercalcemia 1 5.00 Pressure And Volume Under Development 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Thus, these studies all provide firm evidence for the decreased of vasopressin-regulated water channel AQP2 expression and the significant defects in the collecting duct of the kidneys from CRF.

vasopressin Regulation (regulated) of Gene_expression (expression) of AQP2 in duct associated with chronic renal failure

1) Confidence 0.04 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2808601 Disease Relevance 0.81 Pain Relevance 0.05

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