INT293126

Context Info Confidence 0.03 First Reported 2005 Last Reported 2005 Negated 0 Speculated 1 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.36 Pain Relevance 0.14

aging (Agtr1a, Aqp2) cytoplasm (Agtr1a, Aqp2) signal transducer activity (Agtr1a, Avp) plasma membrane (Agtr1a, Aqp2) endosome (Agtr1a) Golgi apparatus (Agtr1a)

Agtr1a (Rattus norvegicus) Avp (Rattus norvegicus) Aqp2 (Rattus norvegicus)

Pain Link Frequency Relevance Heat bradykinin 1 97.64 antagonist 3 92.32 isoflurane 4 32.40 anesthesia 3 5.00 fibrosis 1 5.00 medulla 1 5.00

Disease Link Frequency Relevance Heat Chronic Renal Failure 124 98.68 Hypertrophy 11 75.48 Uremia 4 5.00 Natriuresis 2 5.00 Fibrosis 1 5.00 Disorders Of Creatine Metabolism 1 5.00 Bartter Syndrome 1 5.00 Hypercalcemia 1 5.00 Pressure And Volume Under Development 1 5.00 Targeted Disruption 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In the present study, we aimed to examine the effects of AngII AT1 receptor blockade on the expression of major renal sodium transporters (NHE3, BSC-1, and TSC) and vasopressin-regulated aquaporin-2 (AQP2) in rats with an early stage of CRF induced by 5/6 nephrectomy.

AT1 receptor Spec (examine) Regulation (effects) of vasopressin Regulation (regulated) of AQP2 associated with chronic renal failure

1) Confidence 0.03 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2808601 Disease Relevance 0.36 Pain Relevance 0.14

General Comments

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