INT294210

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ldlr) transport (Ldlr) cytoplasm (Plat)
lipid metabolic process (Ldlr) peptidase activity (Plat) extracellular space (Plat)
Anatomy Link Frequency
brain 1
Ldlr (Mus musculus)
Plat (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 1 87.12 High High
Central nervous system 9 45.44 Quite Low
ischemia 5 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stroke 27 56.96 Quite High
Hypoxia 1 30.64 Quite Low
Cancer 1 23.76 Low Low
Necrosis 1 23.28 Low Low
Middle Cerebral Artery Infarction 17 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Apoptosis 5 5.00 Very Low Very Low Very Low
Cicatrix 4 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 4 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to the PA/plasmin system, tPA interacts with other effectors such as low-density lipoprotein receptor-related protein (LRP) [60], [61] and latent platelet-derived growth factor-CC (PDGF-CC) [62], [63] which may subsequently influence the brain ECM remodeling and neurite outgrowth. tPA converts PDGF-CC to an active form PDGF-C, which is expressed in embryonic and adult mouse brain and contributes to brain remodeling and spinal cord development [64].
low-density lipoprotein receptor Binding (interacts) of tPA in brain associated with spinal cord
1) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2815778 Disease Relevance 0.06 Pain Relevance 0.04

General Comments

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