INT294310

Context Info Confidence 0.06 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.12 Pain Relevance 0.08

extracellular space (IL11) extracellular region (IL11) plasma membrane (PTGER2) cell-cell signaling (IL11) cytoplasm (IL11) signal transducer activity (PTGER2)

PTGER2 (Homo sapiens) IL11 (Homo sapiens)

Pain Link Frequency Relevance Heat cytokine 5 84.44 metalloproteinase 2 78.32 Pain 1 5.00

Disease Link Frequency Relevance Heat Adhesions 2 62.64 Female Infertility 1 7.68 Infection 3 5.00 Pain 1 5.00 Hyperplasia 1 5.00 Hematological Disease 1 5.00 Spontaneous Abortion 1 5.00 Down Syndrome 1 5.00 Reprotox - General 3 1 5.00 Neurodegenerative Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

IL-11 is known to enhance progesterone mediated decidualization and that relaxin and PGE2 enhance IL-11 expression (Dimitriadis et al., 2002, 2005a, b).

PGE2 Positive_regulation (enhance) of Gene_expression (expression) of IL-11

1) Confidence 0.06 Published 2010 Journal Molecular Human Reproduction Section Body Doc Link PMC2816169 Disease Relevance 0.12 Pain Relevance 0.08

General Comments

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