INT294675

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Context Info
Confidence 0.78
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.15
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il12b) cytoplasm (Il12b)
Anatomy Link Frequency
monocytes 1
lymphocytes 1
Il12b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 47 91.48 High High
Inflammatory response 6 84.84 Quite High
Inflammation 21 70.32 Quite High
imagery 27 5.00 Very Low Very Low Very Low
Central nervous system 21 5.00 Very Low Very Low Very Low
Pain 18 5.00 Very Low Very Low Very Low
positron emission tomography 12 5.00 Very Low Very Low Very Low
Nerve growth factor 10 5.00 Very Low Very Low Very Low
chemokine 10 5.00 Very Low Very Low Very Low
Peripheral nervous system 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 203 94.48 High High
Cold Sores 367 88.92 High High
Amebiasis 22 85.36 High High
INFLAMMATION 27 84.48 Quite High
Infection 76 66.76 Quite High
Toxicity 14 61.12 Quite High
Parasitemia 1 49.28 Quite Low
Neuroblastoma 2 43.84 Quite Low
Glioma 11 42.76 Quite Low
Necrosis 3 40.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GM-CSF engenders protective immunity by stimulating the recruitment, maturation, and function of DCs, while IL-12 released from DCs directly primes effector lymphocytes at local environments.
Localization (released) of IL-12 in lymphocytes
1) Confidence 0.78 Published 2010 Journal The Open Virology Journal Section Body Doc Link PMC2936037 Disease Relevance 0.77 Pain Relevance 0.11
The interaction of LPPG with TLR2 and TLR4 resulted in activation of NF-kappaB and release of IL-8, IL-10, IL-12p40, and TNF-alpha from human monocytes [85, 96].
Localization (release) of IL-12 in monocytes
2) Confidence 0.68 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2817369 Disease Relevance 0.38 Pain Relevance 0.08

General Comments

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