INT295410

Context Info Confidence 0.00 First Reported 2010 Last Reported 2010 Negated 0 Speculated 1 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

nucleoplasm (Xpo1) cytoplasm (Xpo1) signal transducer activity (Oprk1) protein transporter activity (Xpo1) signal transduction (Oprk1) RNA binding (Xpo1)

Oprk1 (Mus musculus) Xpo1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat dorsal root ganglion 14 5.00 opioid receptor 4 5.00 Dynorphin 3 5.00 Pain 2 5.00

Disease Link Frequency Relevance Heat Ganglion Cysts 14 5.00 Pain 2 5.00 Targeted Disruption 1 5.00 Death 1 5.00 Adhesions 1 5.00 Cognitive Disorder 1 5.00 Stress 1 5.00 Diuresis 1 5.00 Cytomegalovirus Infection 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These data suggest that other factors or molecules might be involved in either promoting KOR mRNA–Grb7–HuR interaction with CRM1 or prohibiting the interaction of Grb7 with the two transportin complexes.

Positive_regulation (promoting) of KOR Spec (might) Binding (interaction) of CRM1

1) Confidence 0.00 Published 2010 Journal The Journal of Cell Biology Section Body Doc Link PMC2819679 Disease Relevance 0 Pain Relevance 0

General Comments

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