INT295685

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.31
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CCL15) extracellular space (CCL15) extracellular region (CCL15)
cell-cell signaling (CCL15)
Anatomy Link Frequency
macrophage 2
CCL15 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 76 100.00 Very High Very High Very High
Inflammation 40 100.00 Very High Very High Very High
chemokine 20 100.00 Very High Very High Very High
fibrosis 1 100.00 Very High Very High Very High
Inflammatory response 2 41.12 Quite Low
metalloproteinase 102 5.00 Very Low Very Low Very Low
COX-2 inhibitor 23 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 44 100.00 Very High Very High Very High
Malignant Neoplastic Disease 4 100.00 Very High Very High Very High
Fibrosis 1 100.00 Very High Very High Very High
Infection 104 99.98 Very High Very High Very High
Herpes Simplex Virus 238 99.78 Very High Very High Very High
Sarcoma 79 50.00 Quite Low
Apoptosis 8 38.84 Quite Low
Adhesions 42 5.00 Very Low Very Low Very Low
Cancer 20 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Compared to uninfected cells, KSHV infection induced the secretion of chemotactic cytokines (chemokines) that mediate leukocyte recruitment to sites of inflammation, fibrosis, and malignancy such as RANTES, macrophage chemoattractant protein-2 (MCP-2), MCP-3, thymus and activation-regulated chemokine (TARC), macrophage inflammatory protein (MIP-1?)
Positive_regulation (induced) of Localization (secretion) of macrophage inflammatory protein in macrophage associated with fibrosis, chemokine, malignant neoplastic disease, inflammation, herpes simplex virus, infection and cytokine
1) Confidence 0.05 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2820536 Disease Relevance 1.31 Pain Relevance 0.91

General Comments

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