INT295869

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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (VEGFA, Srsf1) nucleoplasm (Srsf1) extracellular space (VEGFA)
extracellular region (VEGFA) growth (VEGFA) proteinaceous extracellular matrix (VEGFA)
VEGFA (Homo sapiens)
Srsf1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 2 28.20 Quite Low
anesthesia 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 2 37.12 Quite Low
Retinal Neovascularization 6 31.60 Quite Low
Hypoxia 4 10.88 Low Low
Cancer 14 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 10 5.00 Very Low Very Low Very Low
Diabetic Retinopathy 10 5.00 Very Low Very Low Very Low
Skin Cancer 4 5.00 Very Low Very Low Very Low
Glaucoma 4 5.00 Very Low Very Low Very Low
Pathologic Neovascularization 4 5.00 Very Low Very Low Very Low
Colon Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fig. 5B shows that in cells treated with PMA, more ASF/SF2 binds to the VEGF construct than in untreated cells.
VEGF Binding (binds) of ASF/SF2
1) Confidence 0.17 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2820781 Disease Relevance 0 Pain Relevance 0
We have shown that ASF/SF2 requires this sequence, which contains both a U2AF65 and consensus ASF/SF2 sequence, for binding to the VEGF pre-mRNA, but does not demonstrate that this is the sequence it binds to.
VEGF Binding (binding) of ASF/SF2
2) Confidence 0.13 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2820781 Disease Relevance 0 Pain Relevance 0

General Comments

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