INT296273

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.62
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Prkaca, Camk4) nucleus (Prkaca, Camk4) kinase activity (Prkaca, Camk4)
mitochondrion (Prkaca) Golgi apparatus (Prkaca) protein complex (Prkaca)
Anatomy Link Frequency
nucleus 4
Prkaca (Mus musculus)
Camk4 (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 40 91.12 High High
Neurotransmitter 2 68.08 Quite High
Lasting pain 4 63.12 Quite High
drug abuse 2 62.56 Quite High
potassium channel 4 61.04 Quite High
Central nervous system 4 56.16 Quite High
depression 62 50.00 Quite Low
antagonist 10 50.00 Quite Low
nMDA receptor 106 49.68 Quite Low
Hippocampus 24 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Brain Disease 2 64.48 Quite High
Anxiety Disorder 48 63.48 Quite High
Pain 6 63.12 Quite High
Drug Dependence 2 62.56 Quite High
Depression 62 50.00 Quite Low
Targeted Disruption 42 28.24 Quite Low
Shock 18 5.00 Very Low Very Low Very Low
Nociception 6 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both PKA and CaMKIV regulate the activation of CREB in the nucleus either through the subunit translocation (in case of PKA) or the entry of CaM (CaMKIV) [28-30].
PKA Regulation (regulate) of Localization (translocation) of CaMKIV in nucleus
1) Confidence 0.16 Published 2010 Journal Mol Brain Section Body Doc Link PMC2822766 Disease Relevance 0.31 Pain Relevance 0.28
Both PKA and CaMKIV regulate the activation of CREB in the nucleus either through the subunit translocation (in case of PKA) or the entry of CaM (CaMKIV) [28-30].
PKA Regulation (regulate) of Localization (translocation) of CaMKIV in nucleus
2) Confidence 0.16 Published 2010 Journal Mol Brain Section Body Doc Link PMC2822766 Disease Relevance 0.31 Pain Relevance 0.28

General Comments

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