INT296439

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Context Info
Confidence 0.41
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.10
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Gria2) endoplasmic reticulum (Gria2) plasma membrane (Gria2)
protein complex (Gria2)
Gria2 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 8 99.04 Very High Very High Very High
Kinase C 18 91.24 High High
Hippocampus 55 82.32 Quite High
agonist 1 70.20 Quite High
spinal dorsal horn 7 63.20 Quite High
antagonist 5 60.40 Quite High
Dorsal horn 6 56.96 Quite High
Glutamate receptor 12 51.20 Quite High
Spinal cord 10 48.88 Quite Low
projection neuron 1 22.72 Low Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 28 97.48 Very High Very High Very High
Nociception 26 45.20 Quite Low
Depression 2 9.60 Low Low
Convulsion 7 6.88 Low Low
Shock 27 5.00 Very Low Very Low Very Low
Pain 11 5.00 Very Low Very Low Very Low
Targeted Disruption 10 5.00 Very Low Very Low Very Low
INFLAMMATION 9 5.00 Very Low Very Low Very Low
Inflammatory Pain 9 5.00 Very Low Very Low Very Low
Hyperalgesia 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that deletion of GluR2 was more effective at blocking initial learning in context A than subsequent learning in context B (significant context x genotype interaction (F (1, 47) ?
Negative_regulation (effective) of Localization (deletion) of GluR2
1) Confidence 0.41 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2947514 Disease Relevance 0.10 Pain Relevance 0.07
In the CNS, GluR1 and GluR2 subunits are ubiquitously expressed and are present in most AMPA receptors in the adult mammalian CNS.
Negative_regulation (present) of Localization (receptors) of AMPA associated with central nervous system
2) Confidence 0.33 Published 2010 Journal Mol Pain Section Body Doc Link PMC2823608 Disease Relevance 0 Pain Relevance 0.34

General Comments

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