INT296446

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.55
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Gria2, Gria4) plasma membrane (Gria2, Gria4) endoplasmic reticulum (Gria2)
protein complex (Gria2)
Anatomy Link Frequency
spinal 1
Gria2 (Mus musculus)
Gria4 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 36 98.80 Very High Very High Very High
Central nervous system 16 98.56 Very High Very High Very High
Spinal cord 20 79.84 Quite High
agonist 2 77.76 Quite High
Dorsal horn neuron 12 66.56 Quite High
Glutamate receptor 22 58.76 Quite High
spinal dorsal horn 14 54.16 Quite High
Inflammation 18 48.56 Quite Low
Dorsal horn 12 47.92 Quite Low
Glutamate 4 20.88 Low Low
Disease Link Frequency Relevance Heat
Nociception 52 99.00 Very High Very High Very High
Hypersensitivity 4 73.48 Quite High
INFLAMMATION 18 48.56 Quite Low
Depression 4 17.16 Low Low
Pain 16 15.12 Low Low
Neuropathic Pain 8 9.88 Low Low
Inflammatory Pain 18 8.88 Low Low
Hyperalgesia 10 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Nervous System Injury 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, Polgar et al. reported that postsynaptic GluR4-containing AMPA receptors were involved in spinal nociceptive transmission [48].
AMPA Binding (receptors) of GluR4 in spinal associated with nociception
1) Confidence 0.13 Published 2010 Journal Mol Pain Section Body Doc Link PMC2823608 Disease Relevance 0.50 Pain Relevance 0.26
AMPA receptors are heteromeric molecules comprising various combinations of GluR1, GluR2, GluR3, and GluR4 subunits.
AMPA Binding (combinations) of GluR4
2) Confidence 0.11 Published 2010 Journal Mol Pain Section Body Doc Link PMC2823608 Disease Relevance 0.05 Pain Relevance 0.32

General Comments

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