INT296454

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Context Info
Confidence 0.30
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Camk2a, Gria2) transport (Gria2) endoplasmic reticulum (Gria2)
protein complex (Gria2) kinase activity (Camk2a) cytoplasm (Camk2a)
Camk2a (Mus musculus)
Gria2 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 18 98.60 Very High Very High Very High
central sensitization 9 70.64 Quite High
Spinal cord 10 57.04 Quite High
Hippocampus 7 41.76 Quite Low
Glutamate receptor 11 38.60 Quite Low
Dorsal horn neuron 6 35.28 Quite Low
Pain 10 16.84 Low Low
IPN 9 5.00 Very Low Very Low Very Low
Inflammation 9 5.00 Very Low Very Low Very Low
Central nervous system 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nociception 26 76.32 Quite High
Pain 8 16.84 Low Low
INFLAMMATION 9 5.00 Very Low Very Low Very Low
Inflammatory Pain 9 5.00 Very Low Very Low Very Low
Hyperalgesia 5 5.00 Very Low Very Low Very Low
Neuropathic Pain 4 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Nervous System Injury 2 5.00 Very Low Very Low Very Low
Hypersensitivity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CaMKII was also found to phosphorylate Serine831 in GluR1 and contributes to the single-channel conductance of the receptor and may increase AMPA receptor conductance during LTP [35,40].
CaMKII Spec (may) Positive_regulation (increase) of Gene_expression (conductance) of AMPA receptor
1) Confidence 0.30 Published 2010 Journal Mol Pain Section Body Doc Link PMC2823608 Disease Relevance 0.14 Pain Relevance 0.24

General Comments

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