INT296856

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.08
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mtor) mitochondrion (Mtor) Golgi apparatus (Mtor)
endoplasmic reticulum (Mtor) nucleus (Mtor) kinase activity (Mtor)
Anatomy Link Frequency
neurons 2
brains 2
Mtor (Mus musculus)
Pain Link Frequency Relevance Heat
Pyramidal cell 12 90.12 High High
Hippocampus 10 5.00 Very Low Very Low Very Low
Limbic system 6 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Locus ceruleus 2 5.00 Very Low Very Low Very Low
Neurobehavioral 2 5.00 Very Low Very Low Very Low
Substantia nigra 2 5.00 Very Low Very Low Very Low
Immobilon 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 118 98.48 Very High Very High Very High
Aging 4 94.36 High High
Movement Disorders 4 93.84 High High
Neurodegenerative Disease 18 93.68 High High
Dementia 18 92.92 High High
Disease 110 90.84 High High
Lewy Body Disease 12 80.32 Quite High
Infection 10 22.76 Low Low
Targeted Disruption 20 5.00 Very Low Very Low Very Low
Gauchers Disease 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The increased levels of mTor and reduced Atg7 levels suggest there may be altered activation of the autophagy pathway in the brains of DLB patients.
Negative_regulation (reduced) of Gene_expression (levels) of mTor in brains associated with parkinson's disease
1) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824828 Disease Relevance 0.90 Pain Relevance 0.09
-syn tg mice levels of mTor were elevated and Atg7 expression was reduced. mTor and LC3 was co-localized with neurons displaying ?
Negative_regulation (reduced) of Gene_expression (expression) of mTor in neurons
2) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824828 Disease Relevance 1.18 Pain Relevance 0

General Comments

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