INT296983

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.56
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (SLC2A4) small molecule metabolic process (SLC2A4) plasma membrane (SLC2A4)
carbohydrate metabolic process (SLC2A4) transmembrane transport (SLC2A4) cytoplasm (SLC2A4)
Anatomy Link Frequency
fat cells 1
SLC2A4 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
behavioral therapy 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 250 97.64 Very High Very High Very High
Hyperinsulinism 2 97.04 Very High Very High Very High
Targeted Disruption 18 95.92 Very High Very High Very High
Weight Loss 4 5.00 Very Low Very Low Very Low
Impaired Glucose Tolerance 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low
Thinness 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Gallstones 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RIP140 silencing significantly increased mRNA levels of GLUT4 and UCP-1 compared to control cells (P < 0.01 for both) (Figure 4C).
Transcription (levels) of GLUT4
1) Confidence 0.37 Published 2010 Journal BMC Endocr Disord Section Body Doc Link PMC2825205 Disease Relevance 0.58 Pain Relevance 0
Furthermore, we observed that primarily mRNA levels of the glucose transporter GLUT4 but not GLUT1 were increased by RIP140 silencing in human fat cells, which is in line with data from knock out mice [5].
Transcription (levels) of GLUT4 in fat cells associated with targeted disruption and obesity
2) Confidence 0.37 Published 2010 Journal BMC Endocr Disord Section Body Doc Link PMC2825205 Disease Relevance 0.98 Pain Relevance 0

General Comments

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