INT297304

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Context Info
Confidence 0.21
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.08
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Icam1) cell adhesion (Icam1) plasma membrane (Icam1)
Icam1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 5 99.90 Very High Very High Very High
ischemia 26 96.12 Very High Very High Very High
Inflammation 66 86.60 High High
Inflammatory response 12 82.88 Quite High
Substantia nigra 74 82.48 Quite High
Inflammatory stimuli 1 77.92 Quite High
dopaminergic neurodegeneration 10 50.00 Quite Low
chemokine 24 29.72 Quite Low
cytokine 43 5.00 Very Low Very Low Very Low
Dopamine 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 16 100.00 Very High Very High Very High
INFLAMMATION 84 99.70 Very High Very High Very High
Cv Unclassified Under Development 26 96.12 Very High Very High Very High
Injury 167 90.60 High High
Endotoxemia 6 41.76 Quite Low
Congenital Anomalies 1 7.28 Low Low
Disease 60 5.00 Very Low Very Low Very Low
Parkinson's Disease 24 5.00 Very Low Very Low Very Low
Targeted Disruption 13 5.00 Very Low Very Low Very Low
Renal Disease 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B on downstream inflammatory mediators, we studied the abundance of the mRNA for intercellular adhesion molecule 1 (ICAM-1), which contains a consensus sequence for binding of NF-?
Regulation (studied) of Transcription (abundance) of ICAM-1 associated with inflammatory mediators and adhesions
1) Confidence 0.21 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC2975641 Disease Relevance 0.25 Pain Relevance 0.15
B on downstream inflammatory mediators, we studied the abundance of the mRNA for intercellular adhesion molecule 1 (ICAM-1), which contains a consensus sequence for binding of NF-?
Regulation (studied) of Transcription (abundance) of intercellular adhesion molecule 1 associated with inflammatory mediators and adhesions
2) Confidence 0.21 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC2975641 Disease Relevance 0.25 Pain Relevance 0.15
Pretreatment with topical polyethylene glycol hydrogel delivery of ICAM-1 antisense oligonucleotides demonstrated decreased ICAM-1 mRNA expression, reduced ICAM-1 protein staining, and decreased cellular damage in a murine partial nephrectomy/ischemia model [74].
Regulation (demonstrated) of Transcription (expression) of ICAM-1 associated with ischemia
3) Confidence 0.21 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2825552 Disease Relevance 1.58 Pain Relevance 0.29

General Comments

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