INT297808

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Context Info
Confidence 0.21
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Nanos2) RNA binding (Nanos2) cytoplasm (Nanos2)
Anatomy Link Frequency
brain 2
Nanos2 (Mus musculus)
Pain Link Frequency Relevance Heat
member 8 2 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Substantia nigra 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Serotonin 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 4 99.64 Very High Very High Very High
Male Infertility 1 98.22 Very High Very High Very High
Starvation 23 81.20 Quite High
Stress 11 43.92 Quite Low
Hypothermia 2 20.36 Low Low
Syndrome 21 5.00 Very Low Very Low Very Low
Hyperphagia 8 5.00 Very Low Very Low Very Low
Obesity 5 5.00 Very Low Very Low Very Low
Failure To Thrive 4 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The function of Nanos2 in brain development is unknown, as the Nanos2 knock-out mice were apparently normal except for male infertility [25], and no phenotypic abnormality was reported for Nanos2 transgenic mice, which over-express Nanos2 under the control of Oct4DeltaPE promoter, but the expression was not examined in brain [27].
Regulation (under) of Gene_expression (express) of Nanos2 in brain associated with targeted disruption and male infertility
1) Confidence 0.21 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2827556 Disease Relevance 0.58 Pain Relevance 0

General Comments

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