INT298468

Context Info Confidence 0.10 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.20 Pain Relevance 1.08

endoplasmic reticulum (Gimap1)

Anatomy Link Frequency skin 2 Gimap1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat inferior alveolar nerve 302 100.00 anesthesia 4 47.84 halothane 4 45.36 fifth nerve 4 38.72 trigeminal ganglion 132 36.16 tetrodotoxin 116 5.00 Action potential 44 5.00 Pain 18 5.00 hyperexcitability 16 5.00 c fibre 14 5.00

Disease Link Frequency Relevance Heat Hypersensitivity 4 99.44 Ganglion Cysts 138 36.16 Nervous System Injury 34 5.00 Pain 20 5.00 Neuropathic Pain 16 5.00 Injury 12 5.00 Congenital Anomalies 4 5.00 Camurati-engelmann Disease 2 5.00 Headache 2 5.00 Wound Healing 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We used IAN-transected rats which showed hypersensitivity to mechanical stimulation of the mental skin and IAN-transected rats without behavior changes which did not show any behavioral changes after IAN transection for single fiber recording experiments.

Positive_regulation (used) of Gene_expression (rats) of IAN-transected in skin associated with inferior alveolar nerve and hypersensitivity

1) Confidence 0.10 Published 2010 Journal Mol Pain Section Body Doc Link PMC2829527 Disease Relevance 0.10 Pain Relevance 0.55

Single fiber recording after IAN transection

Positive_regulation (after) of Gene_expression (transection) of IAN associated with inferior alveolar nerve

2) Confidence 0.10 Published 2010 Journal Mol Pain Section Body Doc Link PMC2829527 Disease Relevance 0.10 Pain Relevance 0.54

General Comments

This test has worked.