INT298829

Context Info Confidence 0.00 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.39 Pain Relevance 0.11

cytosol (SUGT1) mitosis (SUGT1) small molecule metabolic process (LCT) plasma membrane (LCT) carbohydrate metabolic process (LCT)

Anatomy Link Frequency intestinal cells 1 LCT (Homo sapiens) SUGT1 (Homo sapiens)

Pain Link Frequency Relevance Heat nud 1 73.04 abdominal pain 1 72.20

Disease Link Frequency Relevance Heat Malabsorption Syndromes 2 94.72 Dyspepsia 1 73.04 Diarrhoea 3 72.64 Abdominal Pain 1 72.20 Obesity 41 36.88 Cancer 4 5.00 Metabolic Syndrome 3 5.00 Disease 2 5.00 Nicotine Addiction 1 5.00 Hypertension 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The T allele correlated perfectly with the LP phenotype of intestinal cells and functional studies have shown that the T allele is associated with the disrupted down-regulation of the LCT gene during childhood (2,3).

LCT Binding (associated) of allele in intestinal cells

1) Confidence 0.00 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2830824 Disease Relevance 0.39 Pain Relevance 0.11

General Comments

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