INT298892

Context Info Confidence 0.58 First Reported 2010 Last Reported 2010 Negated 0 Speculated 1 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.54 Pain Relevance 0

Golgi apparatus (RAB7A) GTPase activity (RAB7A) lysosome (RAB7A)

Anatomy Link Frequency HeLa 2 RAB7A (Homo sapiens)

Pain Link Frequency Relevance Heat imagery 5 5.00 Pain 3 5.00 Congenital analgesia 1 5.00 Demyelination 1 5.00 Nerve growth factor 1 5.00 Peripheral nervous system 1 5.00

Disease Link Frequency Relevance Heat Disease 76 99.78 Charcot Marie Tooth Disease 6 5.00 Neurodegenerative Disease 4 5.00 Pain 4 5.00 Neurological Disease 2 5.00 Syndrome 2 5.00 Mouth Disease 2 5.00 Ulcers 1 5.00 Demyelinating Disease 1 5.00 Muscle Weakness 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

To determine whether disease mutations affect Rab7 subcellular localization, we analyzed the distribution of GFP-tagged Rab7 in HeLa cells.

Spec (whether) Regulation (affect) of Localization (localization) of Rab7 in HeLa associated with disease

1) Confidence 0.58 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2830827 Disease Relevance 0.54 Pain Relevance 0

General Comments

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