INT298926

Context Info Confidence 0.08 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.46 Pain Relevance 0

cytosol (ARHGEF2) mitosis (ARHGEF2) cell morphogenesis (ARHGEF2) Golgi apparatus (ARHGEF2) plasma membrane (ARHGEF2) cytoskeleton (ARHGEF2)

ARHGEF2 (Homo sapiens)

Pain Link Frequency Relevance Heat imagery 5 5.00 Pain 3 5.00 Congenital analgesia 1 5.00 Demyelination 1 5.00 Nerve growth factor 1 5.00 Peripheral nervous system 1 5.00

Disease Link Frequency Relevance Heat Disease 76 97.84 Charcot Marie Tooth Disease 6 5.00 Neurodegenerative Disease 4 5.00 Pain 4 5.00 Neurological Disease 2 5.00 Syndrome 2 5.00 Mouth Disease 2 5.00 Ulcers 1 5.00 Demyelinating Disease 1 5.00 Muscle Weakness 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These properties render Rabs, including Rab7, dependent on the positive and negative influences of regulatory GEF and GAP proteins.

Regulation (dependent) of Negative_regulation (influences) of GEF

1) Confidence 0.08 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2830827 Disease Relevance 0.46 Pain Relevance 0

General Comments

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