INT299456

Context Info Confidence 0.21 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.09 Pain Relevance 0

nucleus (Gabpa, Notch1) cell differentiation (Notch1) Golgi apparatus (Notch1) plasma membrane (Notch1) embryo development (Notch1) DNA binding (Gabpa)

Gabpa (Mus musculus) Notch1 (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 1 31.88 Inflammation 1 31.48 Pain 1 21.64 Dopamine 1 5.00 adenocard 1 5.00

Disease Link Frequency Relevance Heat Targeted Disruption 7 85.24 Adhesions 2 49.56 Apoptosis 2 35.76 INFLAMMATION 1 31.48 Fibrosarcoma 1 25.28 Pain 1 21.64 Repression 13 5.00 Syndrome 6 5.00 Premature Ovarian Failure 5 5.00 Ocular Toxicity (including Many Sub-types) 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In the regulation of the nicotinic acetylcholine receptor gene, Gabpa recruits the histone acetyl transferase p300 when the promoter is activated, and recruits the histone deacetylase HDAC1 when the promoter is not activated [35].

Gabpa Binding (recruits) of p300

1) Confidence 0.21 Published 2010 Journal J Ovarian Res Section Body Doc Link PMC2831895 Disease Relevance 0.09 Pain Relevance 0

General Comments

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