INT299783

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Line 7: Line 7:
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Confidence
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Confidence
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.3651028500
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.14
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2005
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2005|2005]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
Line 22: Line 22:
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Reported most in
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Reported most in
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| NULL
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| Body
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Documents
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Documents
Line 29: Line 29:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Total Number
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Total Number
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 8
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 8
 +
|-
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Disease Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 6.49
 +
|-
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Pain Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 2.49
 
|-
 
|-
 
|}
 
|}
Line 42: Line 48:
 
fontcolor=white,
 
fontcolor=white,
 
label="Binding",
 
label="Binding",
URL=Binding
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=E:Binding"
 
];
 
];
 
node2
 
node2
Line 50: Line 56:
 
fontcolor=white,
 
fontcolor=white,
 
label="Cd28",
 
label="Cd28",
URL="Cd28"
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=G:12487"
 
];
 
];
 
node3
 
node3
Line 58: Line 64:
 
fontcolor=white,
 
fontcolor=white,
 
label="Cd80",
 
label="Cd80",
URL="Cd80"
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=G:12519"
 
];
 
];
 
subgraph cluster_0 {
 
subgraph cluster_0 {
Line 72: Line 78:
 
{| cellspacing=5 cellpadding=2
 
{| cellspacing=5 cellpadding=2
 
|-
 
|-
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[plasma membrane]] ([[Cd28]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:plasma membrane|plasma membrane]] ([[G:12487|Cd28]])
 
|-
 
|-
 
|}
 
|}
Line 80: Line 86:
 
{| cellpadding=3 cellspacing=0  
 
{| cellpadding=3 cellspacing=0  
 
|-
 
|-
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Anatomy Mention
+
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Anatomy Link
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Frequency
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Frequency
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:1767|T cell]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:T cell|T cell]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|2
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|2
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:456|macrophages]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:macrophages|macrophages]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:764|B cells]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:B cells|B cells]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
|-
 
|-
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[anat:2100|dendritic cells]]
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| [[A:dendritic cells|dendritic cells]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"|1
 
|-
 
|-
Line 103: Line 109:
 
|-
 
|-
 
|}
 
|}
 +
 
|-
 
|-
|colspan="3"|
+
|}
{| cellspacing=1 cellpadding=1
+
{| cellspacing=2 cellpadding=2
|
+
| style="vertical-align: top"|
 
{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
| style="color: black; background:#AAFCFB; white-space:wrap;"| '''Pain Relations:'''
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Link
(frequency)
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[abatacept]] (242)
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
{{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Infliximab]] (2)
+
{{#icon: chilli.png|Quite High}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Inflammation]] (8)
+
{{#icon: chilli.png|Quite High}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Corticosteroids]] (12)
+
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[methotrexate]] (42)
+
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[cytokines]] (32)
+
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[withdrawal]] (6)
+
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[painful]] (6)
+
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
 
|-
 
|-
| style="color: black; background:#AAFCFB; white-space:wrap;"| '''Disease Relations:'''
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Arthritis|Arthritis]]
(frequency)
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 108
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Arthropathy]] (8)
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.64
{{#icon: chilli.png|Quite High}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[INFLAMMATION]] (8)
+
{{#icon: chilli.png|Quite High}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Apoptosis]] (12)
+
{{#icon: chilli.png|Quite High}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Death]] (6)
+
{{#icon: chilli.png|Quite High}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Demyelinating Disease]] (6)
+
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Necrosis]] (12)
+
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Staphylococcus Infection]] (6)
+
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Mycobacterial Infection]] (2)
+
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
|}
+
{| cellpadding=3 cellspacing=0
+
 
|-
 
|-
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Protein
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:rheumatoid arthritis|rheumatoid arthritis]]
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Mutation
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 182
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Frequency
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.36
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:cytokine|cytokine]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 32
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 91.40
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:abatacept|abatacept]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 242
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 88.52
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:tolerance|tolerance]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 28
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 84.24
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Infliximab|Infliximab]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 82.36
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Inflammation|Inflammation]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 68.76
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Multiple sclerosis|Multiple sclerosis]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 47.84
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:cva|cva]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 4
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 25.12
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:corticosteroid|corticosteroid]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 12
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 18.72
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Low}} {{#icon: cold.png|Low}}
 
|-
 
|-
  
 
|}
 
|}
 +
|
 +
| style="vertical-align: top"|
 +
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
|}
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Link
 +
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 +
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 +
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Arthritis|Arthritis]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 52
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.64
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Apoptosis|Apoptosis]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 12
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.64
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Rheumatoid Arthritis|Rheumatoid Arthritis]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 182
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 98.36
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Immunization|Immunization]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 34
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 94.04
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Experimental Arthritis|Experimental Arthritis]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 58
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 89.04
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Ankylosis|Ankylosis]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 87.60
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Disease|Disease]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 134
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 84.32
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Arthropathy|Arthropathy]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 75.72
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Death|Death]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 69.04
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:INFLAMMATION|INFLAMMATION]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 68.76
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 +
|-
 +
|}
 
|}
 
|}
  
Line 166: Line 241:
 
| style="color: black; background:white; white-space:wrap;"| Key:
 
| style="color: black; background:white; white-space:wrap;"| Key:
 
| style="color: black; background:#FFFF00; border: 1px solid lightgray; white-space:wrap;"| Protein
 
| style="color: black; background:#FFFF00; border: 1px solid lightgray; white-space:wrap;"| Protein
 +
| style="color: black; background:#ADFF2F; border: 1px solid lightgray; white-space:wrap;"| Mutation
 
| style="color: black; background:#B0E0E6; border: 1px solid lightgray; white-space:wrap;"| Event
 
| style="color: black; background:#B0E0E6; border: 1px solid lightgray; white-space:wrap;"| Event
 
| style="color: black; background:#FFDEAD; border: 1px solid lightgray; white-space:wrap;"| Anatomy
 
| style="color: black; background:#FFDEAD; border: 1px solid lightgray; white-space:wrap;"| Anatomy
Line 171: Line 247:
 
| style="color: black; background:#D3D3D3; border: 1px solid lightgray; white-space:wrap;"| Speculation
 
| style="color: black; background:#D3D3D3; border: 1px solid lightgray; white-space:wrap;"| Speculation
 
| style="color: black; background:#FFA07A; border: 1px solid lightgray; white-space:wrap;"| Pain term
 
| style="color: black; background:#FFA07A; border: 1px solid lightgray; white-space:wrap;"| Pain term
 +
| style="color: black; background:#FFA07A; border: 1px solid lightgray; white-space:wrap;"| Disease term
 
|-
 
|-
 
|}
 
|}
Line 179: Line 256:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''CD28'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">interaction</span>) of <span style="color:#800000">'''CD80'''</span> in <span style="color:#808000">T cell</span>
+
|  [[G:12487|<span style="color:#800000">'''CD28'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">interaction</span>) of [[G:12519|<span style="color:#800000">'''CD80'''</span>]] in [[A:T cell|<span style="color:#808000">T cell</span>]]
 
|-
 
|-
 
|}
 
|}
Line 188: Line 265:
 
! style="color: black; background:white; white-space:nowrap;"| 1)
 
! style="color: black; background:white; white-space:nowrap;"| 1)
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Confidence
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Confidence
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.140812717444618
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.14
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Section
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Section
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| Body
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Doc Link
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Doc Link
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2875641 PMC2875641]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2875641 PMC2875641]
 +
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 1.00
 +
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.49
 
|}
 
|}
 
|-
 
|-
Line 206: Line 287:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''CD28'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">interaction</span>) of <span style="color:#800000">'''CD80'''</span> in <span style="color:#808000">T cell</span>
+
|  [[G:12487|<span style="color:#800000">'''CD28'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">interaction</span>) of [[G:12519|<span style="color:#800000">'''CD80'''</span>]] in [[A:T cell|<span style="color:#808000">T cell</span>]]
 
|-
 
|-
 
|}
 
|}
Line 215: Line 296:
 
! style="color: black; background:white; white-space:nowrap;"| 2)
 
! style="color: black; background:white; white-space:nowrap;"| 2)
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Confidence
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Confidence
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.140812717444618
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.14
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2010
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2010|2010]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Section
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Section
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| Body
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Doc Link
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Doc Link
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2875641 PMC2875641]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2875641 PMC2875641]
 +
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 1.00
 +
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.49
 
|}
 
|}
 
|-
 
|-
 
|}
 
|}
 
{| style="color: black; background-color: white;" cellpadding=6 cellspacing=6 class="wikitable"
 
{| style="color: black; background-color: white;" cellpadding=6 cellspacing=6 class="wikitable"
| These observations suggest that <span style="background-color:#FFFF00">CD28</span>–<span style="background-color:#FFFF00">CD80</span>/86 <span style="background-color:#B0E0E6">interactions</span> are important in the initiation of the arthritis.  
+
| These observations suggest that <span style="background-color:#FFFF00">CD28</span>–<span style="background-color:#FFFF00">CD80</span>/86 <span style="background-color:#B0E0E6">interactions</span> are important in the initiation of the <span style="background-color:#FFA07A">arthritis</span>.  
 
|-
 
|-
 
|
 
|
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''CD28'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">interactions</span>) of <span style="color:#800000">'''CD80'''</span>
+
|  [[G:12487|<span style="color:#800000">'''CD28'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">interactions</span>) of [[G:12519|<span style="color:#800000">'''CD80'''</span>]] associated with <span style="color:#FF0000">'''arthritis'''</span>
 
|-
 
|-
 
|}
 
|}
Line 242: Line 327:
 
! style="color: black; background:white; white-space:nowrap;"| 3)
 
! style="color: black; background:white; white-space:nowrap;"| 3)
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Confidence
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Confidence
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.083477425726812
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.08
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2005
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2005|2005]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Section
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Section
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| Body
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Doc Link
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Doc Link
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2833980 PMC2833980]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2833980 PMC2833980]
 +
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 1.35
 +
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.44
 
|}
 
|}
 
|-
 
|-
 
|}
 
|}
 
{| style="color: black; background-color: white;" cellpadding=6 cellspacing=6 class="wikitable"
 
{| style="color: black; background-color: white;" cellpadding=6 cellspacing=6 class="wikitable"
| These observations suggest that <span style="background-color:#FFFF00">CD28</span>–<span style="background-color:#FFFF00">CD80</span>/86 <span style="background-color:#B0E0E6">interactions</span> are important in the initiation of the arthritis.  
+
| These observations suggest that <span style="background-color:#FFFF00">CD28</span>–<span style="background-color:#FFFF00">CD80</span>/86 <span style="background-color:#B0E0E6">interactions</span> are important in the initiation of the <span style="background-color:#FFA07A">arthritis</span>.  
 
|-
 
|-
 
|
 
|
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''CD28'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">interactions</span>) of <span style="color:#800000">'''CD80'''</span>
+
|  [[G:12487|<span style="color:#800000">'''CD28'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">interactions</span>) of [[G:12519|<span style="color:#800000">'''CD80'''</span>]] associated with <span style="color:#FF0000">'''arthritis'''</span>
 
|-
 
|-
 
|}
 
|}
Line 269: Line 358:
 
! style="color: black; background:white; white-space:nowrap;"| 4)
 
! style="color: black; background:white; white-space:nowrap;"| 4)
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Confidence
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Confidence
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.083477425726812
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.08
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2005
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2005|2005]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Section
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Section
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| Body
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Doc Link
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Doc Link
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2833980 PMC2833980]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2833980 PMC2833980]
 +
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 1.35
 +
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.44
 
|}
 
|}
 
|-
 
|-
Line 287: Line 380:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''CD28'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">interactions</span>) of <span style="color:#800000">'''CD80'''</span>
+
|  [[G:12487|<span style="color:#800000">'''CD28'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">interactions</span>) of [[G:12519|<span style="color:#800000">'''CD80'''</span>]]
 
|-
 
|-
 
|}
 
|}
Line 296: Line 389:
 
! style="color: black; background:white; white-space:nowrap;"| 5)
 
! style="color: black; background:white; white-space:nowrap;"| 5)
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Confidence
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Confidence
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.083477425726812
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.08
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2005
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2005|2005]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Section
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Section
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| Body
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Doc Link
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Doc Link
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2833980 PMC2833980]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2833980 PMC2833980]
 +
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.44
 +
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.30
 
|}
 
|}
 
|-
 
|-
Line 314: Line 411:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''CD28'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">binds</span>) of <span style="color:#800000">'''CD80'''</span> in <span style="color:#808000">dendritic cells</span>
+
|  [[G:12487|<span style="color:#800000">'''CD28'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">binds</span>) of [[G:12519|<span style="color:#800000">'''CD80'''</span>]] in [[A:dendritic cells|<span style="color:#808000">dendritic cells</span>]]
 
|-
 
|-
 
|}
 
|}
Line 323: Line 420:
 
! style="color: black; background:white; white-space:nowrap;"| 6)
 
! style="color: black; background:white; white-space:nowrap;"| 6)
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Confidence
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Confidence
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.083477425726812
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.08
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2005
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2005|2005]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Section
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Section
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| Body
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Doc Link
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Doc Link
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2833980 PMC2833980]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2833980 PMC2833980]
 +
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.45
 +
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.11
 
|}
 
|}
 
|-
 
|-
Line 341: Line 442:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''CD28'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">binds</span>) of <span style="color:#800000">'''CD80'''</span> in <span style="color:#808000">macrophages</span>
+
|  [[G:12487|<span style="color:#800000">'''CD28'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">binds</span>) of [[G:12519|<span style="color:#800000">'''CD80'''</span>]] in [[A:macrophages|<span style="color:#808000">macrophages</span>]]
 
|-
 
|-
 
|}
 
|}
Line 350: Line 451:
 
! style="color: black; background:white; white-space:nowrap;"| 7)
 
! style="color: black; background:white; white-space:nowrap;"| 7)
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Confidence
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Confidence
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.0283823247471161
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.03
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2005
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2005|2005]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Section
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Section
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| Body
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Doc Link
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Doc Link
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2833980 PMC2833980]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2833980 PMC2833980]
 +
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.45
 +
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.11
 
|}
 
|}
 
|-
 
|-
Line 368: Line 473:
 
{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''CD28'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">binds</span>) of <span style="color:#800000">'''CD80'''</span> in <span style="color:#808000">B cells</span>
+
|  [[G:12487|<span style="color:#800000">'''CD28'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">binds</span>) of [[G:12519|<span style="color:#800000">'''CD80'''</span>]] in [[A:B cells|<span style="color:#808000">B cells</span>]]
 
|-
 
|-
 
|}
 
|}
Line 377: Line 482:
 
! style="color: black; background:white; white-space:nowrap;"| 8)
 
! style="color: black; background:white; white-space:nowrap;"| 8)
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Confidence
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Confidence
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.0283823247471161
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.03
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2005
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2005|2005]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Arthritis Res Ther|Arthritis Res Ther]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Section
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Section
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| N/A
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| Body
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Doc Link
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Doc Link
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2833980 PMC2833980]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [http://www.ncbi.nlm.nih.gov/pubmed?term=PMC2833980 PMC2833980]
 +
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Disease Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.45
 +
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Pain Relevance
 +
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.11
 
|}
 
|}
 
|-
 
|-

Latest revision as of 00:43, 21 September 2012

Context Info
Confidence 0.14
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 8
Disease Relevance 6.49
Pain Relevance 2.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cd28)
Anatomy Link Frequency
T cell 2
macrophages 1
B cells 1
dendritic cells 1
Cd28 (Mus musculus)
Cd80 (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 108 98.64 Very High Very High Very High
rheumatoid arthritis 182 98.36 Very High Very High Very High
cytokine 32 91.40 High High
abatacept 242 88.52 High High
tolerance 28 84.24 Quite High
Infliximab 2 82.36 Quite High
Inflammation 8 68.76 Quite High
Multiple sclerosis 6 47.84 Quite Low
cva 4 25.12 Quite Low
corticosteroid 12 18.72 Low Low
Disease Link Frequency Relevance Heat
Arthritis 52 98.64 Very High Very High Very High
Apoptosis 12 98.64 Very High Very High Very High
Rheumatoid Arthritis 182 98.36 Very High Very High Very High
Immunization 34 94.04 High High
Experimental Arthritis 58 89.04 High High
Ankylosis 6 87.60 High High
Disease 134 84.32 Quite High
Arthropathy 8 75.72 Quite High
Death 6 69.04 Quite High
INFLAMMATION 8 68.76 Quite High

[edit] Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to the CD80/86-CD28 interaction, co-stimulation of T cell responses occurs through the CD40-CD154 interaction between APCs and T cells.
CD28 Binding (interaction) of CD80 in T cell
1) Confidence 0.14 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875641 Disease Relevance 1.00 Pain Relevance 0.49
In addition to the CD80/86-CD28 interaction, co-stimulation of T cell responses occurs through the CD40-CD154 interaction between APCs and T cells.
CD28 Binding (interaction) of CD80 in T cell
2) Confidence 0.14 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875641 Disease Relevance 1.00 Pain Relevance 0.49
These observations suggest that CD28–CD80/86 interactions are important in the initiation of the arthritis.
CD28 Binding (interactions) of CD80 associated with arthritis
3) Confidence 0.08 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833980 Disease Relevance 1.35 Pain Relevance 0.44
These observations suggest that CD28–CD80/86 interactions are important in the initiation of the arthritis.
CD28 Binding (interactions) of CD80 associated with arthritis
4) Confidence 0.08 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833980 Disease Relevance 1.35 Pain Relevance 0.44
The regulatory effects of interrupting CD28 interactions with CD80/86 have been harnessed in recombinant molecules (CTLA4–immunoglobulin [Ig]) that combine the extracellular domain of human CTLA4 with a portion of the Fc domain of IgG1 [10].
CD28 Binding (interactions) of CD80
5) Confidence 0.08 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833980 Disease Relevance 0.44 Pain Relevance 0.30
CD28 is present on most T cells and it binds to both CD80 (B7-1) and CD86 (B7-2), which are present on antigen-presenting cells, including dendritic cells, B cells, and macrophages.
CD28 Binding (binds) of CD80 in dendritic cells
6) Confidence 0.08 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833980 Disease Relevance 0.45 Pain Relevance 0.11
CD28 is present on most T cells and it binds to both CD80 (B7-1) and CD86 (B7-2), which are present on antigen-presenting cells, including dendritic cells, B cells, and macrophages.
CD28 Binding (binds) of CD80 in macrophages
7) Confidence 0.03 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833980 Disease Relevance 0.45 Pain Relevance 0.11
CD28 is present on most T cells and it binds to both CD80 (B7-1) and CD86 (B7-2), which are present on antigen-presenting cells, including dendritic cells, B cells, and macrophages.
CD28 Binding (binds) of CD80 in B cells
8) Confidence 0.03 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833980 Disease Relevance 0.45 Pain Relevance 0.11

[edit] General Comments

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