INT299783

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| style="color: black; background:#AAFCFB; white-space:wrap;"| '''Pain Relations:'''
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! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Term
−
(frequency)
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[abatacept]] (242)
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! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
−
{{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Infliximab]] (2)
+
−
{{#icon: chilli.png|Quite High}}
+
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Inflammation]] (8)
+
−
{{#icon: chilli.png|Quite High}}
+
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Corticosteroids]] (12)
+
−
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[methotrexate]] (42)
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−
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[cytokines]] (32)
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−
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[withdrawal]] (6)
+
−
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[painful]] (6)
+
−
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
 
|-
 
|-
−
| style="color: black; background:#AAFCFB; white-space:wrap;"| '''Disease Relations:'''
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[abatacept]]
−
(frequency)
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 242
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Arthropathy]] (8)
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 88.52
−
{{#icon: chilli.png|Quite High}}
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[INFLAMMATION]] (8)
+
−
{{#icon: chilli.png|Quite High}}
+
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Apoptosis]] (12)
+
−
{{#icon: chilli.png|Quite High}}
+
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Death]] (6)
+
−
{{#icon: chilli.png|Quite High}}
+
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Demyelinating Disease]] (6)
+
−
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Necrosis]] (12)
+
−
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Staphylococcus Infection]] (6)
+
−
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
−
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Mycobacterial Infection]] (2)
+
−
{{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
+
−
|}
+
−
{| cellpadding=3 cellspacing=0
+
 
|-
 
|-
−
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"| Protein
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Infliximab]]
−
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Mutation
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
−
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;" align="center"| Frequency
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 82.36
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Inflammation]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 68.76
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[corticosteroid]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 12
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[methotrexate]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 42
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[cytokine]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 32
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[withdrawal]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Pain]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Etanercept]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 18
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[tolerance]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 28
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
|-
 
|-
  
−
|}
+
|}|
 +
|
 +
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
−
|}
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Term
 +
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 +
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
 +
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Arthropathy]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 69.88
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[INFLAMMATION]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 68.76
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Apoptosis]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 12
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 63.12
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Death]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 61.92
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Demyelinating Disease]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Necrosis]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 12
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Staphylococcus Infection]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 6
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Mycobacterial Infection]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Systemic Lupus Erythematosus]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 12
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Pressure And Volume Under Development]]
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 18
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 +
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 +
|-
 +
|}
 
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Revision as of 12:19, 12 September 2012

Context Info
Confidence 0.3651028500
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in NULL
Documents 7
Total Number 8

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cd28)
Anatomy Mention Frequency
T cell 2
macrophages 1
B cells 1
dendritic cells 1
Cd28 (Mus musculus)
Cd80 (Mus musculus)
Pain Term Frequency Confidence Heat
abatacept 242 88.52 High High
Infliximab 2 82.36 Quite High
Inflammation 8 68.76 Quite High
corticosteroid 12 5 Very Low Very Low Very Low
methotrexate 42 5 Very Low Very Low Very Low
cytokine 32 5 Very Low Very Low Very Low
withdrawal 6 5 Very Low Very Low Very Low
Pain 6 5 Very Low Very Low Very Low
Etanercept 18 5 Very Low Very Low Very Low
tolerance 28 5 Very Low Very Low Very Low
|
Disease Term Frequency Confidence Heat
Arthropathy 8 69.88 Quite High
INFLAMMATION 8 68.76 Quite High
Apoptosis 12 63.12 Quite High
Death 6 61.92 Quite High
Demyelinating Disease 6 5 Very Low Very Low Very Low
Necrosis 12 5 Very Low Very Low Very Low
Staphylococcus Infection 6 5 Very Low Very Low Very Low
Mycobacterial Infection 2 5 Very Low Very Low Very Low
Systemic Lupus Erythematosus 12 5 Very Low Very Low Very Low
Pressure And Volume Under Development 18 5 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Event Anatomy Negation Speculation Pain term
In addition to the CD80/86-CD28 interaction, co-stimulation of T cell responses occurs through the CD40-CD154 interaction between APCs and T cells.
CD28 Binding (interaction) of CD80 in T cell
1) Confidence 0.140812717444618 Published 2010 Journal N/A Section N/A Doc Link PMC2875641
In addition to the CD80/86-CD28 interaction, co-stimulation of T cell responses occurs through the CD40-CD154 interaction between APCs and T cells.
CD28 Binding (interaction) of CD80 in T cell
2) Confidence 0.140812717444618 Published 2010 Journal N/A Section N/A Doc Link PMC2875641
These observations suggest that CD28–CD80/86 interactions are important in the initiation of the arthritis.
CD28 Binding (interactions) of CD80
3) Confidence 0.083477425726812 Published 2005 Journal N/A Section N/A Doc Link PMC2833980
These observations suggest that CD28–CD80/86 interactions are important in the initiation of the arthritis.
CD28 Binding (interactions) of CD80
4) Confidence 0.083477425726812 Published 2005 Journal N/A Section N/A Doc Link PMC2833980
The regulatory effects of interrupting CD28 interactions with CD80/86 have been harnessed in recombinant molecules (CTLA4–immunoglobulin [Ig]) that combine the extracellular domain of human CTLA4 with a portion of the Fc domain of IgG1 [10].
CD28 Binding (interactions) of CD80
5) Confidence 0.083477425726812 Published 2005 Journal N/A Section N/A Doc Link PMC2833980
CD28 is present on most T cells and it binds to both CD80 (B7-1) and CD86 (B7-2), which are present on antigen-presenting cells, including dendritic cells, B cells, and macrophages.
CD28 Binding (binds) of CD80 in dendritic cells
6) Confidence 0.083477425726812 Published 2005 Journal N/A Section N/A Doc Link PMC2833980
CD28 is present on most T cells and it binds to both CD80 (B7-1) and CD86 (B7-2), which are present on antigen-presenting cells, including dendritic cells, B cells, and macrophages.
CD28 Binding (binds) of CD80 in macrophages
7) Confidence 0.0283823247471161 Published 2005 Journal N/A Section N/A Doc Link PMC2833980
CD28 is present on most T cells and it binds to both CD80 (B7-1) and CD86 (B7-2), which are present on antigen-presenting cells, including dendritic cells, B cells, and macrophages.
CD28 Binding (binds) of CD80 in B cells
8) Confidence 0.0283823247471161 Published 2005 Journal N/A Section N/A Doc Link PMC2833980

General Comments

This test has worked.

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